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[原发性孤立性卵巢脓肿。临床与细菌学观察及一种新的发病机制假说(作者译)]

[The primary isolated ovarian abscess. Clinical and bacteriological observations and a new pathogenetic hypothesis (author's transl)].

作者信息

Egger H, Fleischmann H

出版信息

Geburtshilfe Frauenheilkd. 1977 Jul;37(7):625-38.

PMID:885336
Abstract

42 of 86 patients with suppurated ovaries had primary isolated ovarian abscesses (PIOA), 44 secondary tubo-ovarian abscesses (STOA). Parts of ectopic endometrium in the abscess wall could be identified by serial sections in 23 PIOA. With Berlin-blue-staining was a special phenomenon in 28 of 42 PIOA demonstrated: a basal layer of hemosiderophages underlying the abscess membrane. Thus in 36 of 42 PIOA the histogenesis out of cystic ovarian endometriosis or other pathologic ovarian hematomas is assured. The PIOA is a typical major complication of ovarian hematomas, especially in cases of ovarian endometriosis caused by vaginal aplasia (gynatresia). Concomitant salpingitis in PIOA is therefore often better explained as secondary descending infection from pelveoperitonitis. Before laparotomy it is extremely difficult to diagnose PIOA on a clinical basis only. More than laboratory data helps this special consideration if an inflammatory adnexal mass could be or not the result of an ascending infection and if an ovarian endometriosis could exist. Besides the abscesses out of cystic ovarian endometriosis PIOA were observed after hysterectomies and complicated appendectomies possible due to the infection of traumatic ovarian hematomas. The only curative therapy for PIOA is surgery--as soon as possible. Antibiotics are poorly helpful. However the inefficacy of antibiotics usually gives the final indication for laparotomy. Knowing the usual etiology of PIOA out of pathologic (endometriotic) ovarian hematomas we have new guidelines in other clinical problems also: Thus every ovarian endometriosis has to be cured--hormonally or surgically; evacuation of endometriotic cysts during pelvic endoscopy is not a sufficient therapy, for the endometrium would be left in the ovary. During operations provocation of traumatic hematomas of the adnexa should be avoided.

摘要

86例卵巢化脓患者中,42例有原发性孤立性卵巢脓肿(PIOA),44例有继发性输卵管卵巢脓肿(STOA)。在23例PIOA中,通过连续切片可在脓肿壁中识别出部分异位子宫内膜。42例PIOA中有28例经柏林蓝染色显示出一种特殊现象:脓肿膜下有一层含铁血黄素巨噬细胞基层。因此,42例PIOA中有36例可确定其组织发生源于囊性卵巢子宫内膜异位症或其他病理性卵巢血肿。PIOA是卵巢血肿的典型主要并发症,尤其是在阴道发育不全(阴道闭锁)引起的卵巢子宫内膜异位症病例中。因此,PIOA合并的输卵管炎常更好地解释为盆腔腹膜炎的继发性下行感染。仅根据临床情况在剖腹手术前极难诊断PIOA。如果炎性附件包块可能是或不是上行感染的结果以及是否存在卵巢子宫内膜异位症,除了实验室数据外,更多的因素有助于这种特殊的考虑。除了源于囊性卵巢子宫内膜异位症的脓肿外,在子宫切除术后以及因创伤性卵巢血肿感染而可能进行的复杂阑尾切除术后也观察到了PIOA。PIOA唯一的治愈性疗法是手术——尽快进行。抗生素帮助不大。然而,抗生素的无效通常是剖腹手术的最终指征。了解PIOA通常源于病理性(子宫内膜异位性)卵巢血肿的病因,我们在其他临床问题上也有了新的指导原则:因此,每例卵巢子宫内膜异位症都必须通过激素或手术治愈;盆腔内镜检查时排空子宫内膜囊肿并非充分的治疗方法,因为子宫内膜会留在卵巢内。手术期间应避免诱发附件的创伤性血肿。

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