Gribbon E M, Sen S D, Roser B J, Kampinga J
Quadrant Holdings Cambridge Limited, Vaccine Division, England.
Dev Biol Stand. 1996;87:193-9.
Efforts directed towards overcoming the problems of vaccine stability must take cost into consideration. One effective approach is the use of a simple stabilization technology applicable, in principle, to every type of vaccine candidate. Following the lead of Nature, the results in this paper show how such techniques based on trehalose have the potential to transform contemporary vaccine manufacture. The possibilities of novel delivery formats and vaccine combinations, currently not feasible, may now also be realised.
致力于克服疫苗稳定性问题的努力必须考虑成本。一种有效的方法是使用一种原则上适用于每种候选疫苗类型的简单稳定化技术。本文以《自然》杂志为引领，展示了基于海藻糖的此类技术如何有可能变革当代疫苗生产。目前不可行的新型给药形式和疫苗组合的可能性现在也可能得以实现。
