五十岁以下男性的前列腺特异性抗原与前列腺炎
Prostate-specific antigen and prostatitis in men under fifty.
作者信息
Pansadoro V, Emiliozzi P, Defidio L, Scarpone P, Sabatini G, Brisciani A, Lauretti S
机构信息
Department of Urology, S. Camillo Hospital, Rome, Italy.
出版信息
Eur Urol. 1996;30(1):24-7. doi: 10.1159/000474140.
OBJECTIVE
To evaluate the occurrence of increased prostate-specific antigen (PSA) serum concentration in patients with prostatitis and low incidence of benign prostatic hyperplasia and prostatic cancer, PSA was measured in a selected population.
METHODS
PSA levels were evaluated in 72 patients with prostatitis under 50 years of age.
RESULTS
An increased PSA (> 4 ng/ml) was found in 5/7 (71%) patients with acute prostatitis, and in 2/13 (15%) and 2/32 (6%) patients with chronic bacterial and abacterial prostatitis, respectively. No patient with prostatodynia had an increased PSA. In patients with bacterial prostatitis PSA level decreased to normal value after effective antibiotic therapy in most cases.
CONCLUSION
Prostatitis must be considered when using PSA as tumor marker.
目的
为评估前列腺炎患者血清前列腺特异性抗原（PSA）浓度升高的情况以及良性前列腺增生和前列腺癌的低发病率，对选定人群进行了PSA检测。
方法
对72例50岁以下的前列腺炎患者的PSA水平进行了评估。
结果
在7例急性前列腺炎患者中有5例（71%）PSA升高（>4 ng/ml），在13例慢性细菌性前列腺炎患者中有2例（15%）、32例慢性非细菌性前列腺炎患者中有2例（6%）PSA升高。前列腺痛患者中无一例PSA升高。在大多数细菌性前列腺炎患者中，有效抗生素治疗后PSA水平降至正常。
结论
将PSA用作肿瘤标志物时必须考虑前列腺炎。
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