Dixit V P
Indian J Physiol Pharmacol. 1977 Apr-Jun;21(2):113-7.
Rats and mice were vasectomized to study the pathological changes in the development and resolution of vasectomy induced sperm granuloma. Epididymal weights were increased in all groups of vasectomized animals, whereas testicular weights did not change. Granuloma in the form of yellow nodular masses of cysts were present at the lower pole of the epididymis. It consisted of a pool of sperm and other material surrounded by a wall of histocytes or macrophages. The biologic significance of the phenomena has been discussed.
对大鼠和小鼠进行输精管结扎,以研究输精管结扎诱导的精子肉芽肿形成和消退过程中的病理变化。所有输精管结扎动物组的附睾重量均增加,而睾丸重量未发生变化。附睾下极出现黄色结节状囊肿形式的肉芽肿。它由一堆精子和其他物质组成,周围是组织细胞或巨噬细胞构成的壁。已对该现象的生物学意义进行了讨论。