Righetti C A, Tosi L, Zanette G
Servizio di Neurologia, Ospedale S. Cuore di Negrar, Verona, Italy.
Ital J Neurol Sci. 1996 Jun;17(3):193-9. doi: 10.1007/BF01995683.
The diagnostic sensitivity of dermatomal somatosensory evoked potentials (DSEPs) was evaluated in a homogeneous group of fifteen patients with low back pain due to isolated lumbosacral radiculopathy. The normative values from L3 to S1 were defined, as were the parameters of abnormality. In seven patients with pseudoradicular or referred leg pain, a negative neurological examination and images indicative of protrusion or paramedian disc hernia, the DSEPs were normal in six cases and slightly altered in one. In eight patients with deafferentation leg pain, clinical signs of root damage and images indicative of an intraforaminal hernia, the DSEPs showed varying degrees of alteration which could generally be correlated to the severity of the clinical picture. This method can therefore be useful in differentiating pain due to stimulation of the receptors of the osteoarticular structures or the root sheath, in which the DSEPs are normal, from pain due to direct root damage, in which the DSEPs are altered. This functional evaluation of anatomical damage provides further information which may help to achieve a better therapeutic approach.
在一组由15例因单纯腰骶神经根病导致腰痛的患者组成的同质群体中,对皮节体感诱发电位(DSEP)的诊断敏感性进行了评估。确定了从L3至S1的正常数值以及异常参数。在7例患有假性神经根性或牵涉性腿痛、神经系统检查阴性且影像显示有椎间盘突出或旁中央型椎间盘疝的患者中,6例患者的DSEP正常,1例略有改变。在8例患有传入阻滞性腿痛、有神经根损伤临床体征且影像显示椎间孔内疝的患者中,DSEP表现出不同程度的改变,总体上与临床表现的严重程度相关。因此,该方法有助于区分由骨关节结构或神经根鞘受体受刺激引起的疼痛(此时DSEP正常)与由直接神经根损伤引起的疼痛(此时DSEP改变)。这种对解剖损伤的功能评估提供了更多信息,可能有助于实现更好的治疗方法。