Svensson C, Olofsson H
Swedish University of Agricultural Sciences, Skara, Sweden.
Appl Parasitol. 1996 Sep;37(3):168-76.
The excretion of Eimeria oocysts, the faecal dry matter and the weight gain of three groups of 12 calves, were compared during their first 20 days of grazing on a pasture known to have been contaminated with oocysts of Eimeria alabamensis during the previous year. On the day of turnout (day 0) the calves in group 1 were each treated with one bolus per 200 kg bodyweight containing 1.6 g baquiloprim and 14.4 g sulphadimidine. The calves of group 2 received the same treatment on day 3, and the calves of group 3 were left untreated. Eleven of the untreated calves developed clinical coccidiosis due to E. alabamensis and excreted more than 850,000 oocysts/g of faeces 8-10 days after turnout. Seven of the calves in group 1 and five of those in group 2 developed diarrhoea, but it was milder and/or less persistent than in the untreated calves. The treated calves excreted significantly fewer oocysts and lost significantly less weight than the untreated calves. On day 21 all the calves were housed and on day 27 they were challenged with 10 million sporulated oocysts of E. alabamensis and turned out on to the same pasture. Only minor clinical signs were observed in some of the calves, indicating development of immunity in all groups. However, there was a tendency for the calves treated on day 3 to excrete more oocysts and to gain less weight than the other calves.
在前一年已知被阿拉巴马艾美耳球虫卵囊污染的牧场上,对三组每组12头犊牛在放牧的前20天内艾美耳球虫卵囊的排泄量、粪便干物质及体重增加情况进行了比较。在放牧当天(第0天),第1组的犊牛每200公斤体重投喂1丸,每丸含1.6克巴喹普明和14.4克磺胺二甲嘧啶。第2组的犊牛在第3天接受相同处理,第3组的犊牛不做处理。11头未处理的犊牛因阿拉巴马艾美耳球虫感染出现临床球虫病,在放牧后8 - 10天粪便中卵囊排泄量超过850,000个/克。第1组的7头犊牛和第2组的5头犊牛出现腹泻,但比未处理的犊牛症状较轻和/或持续时间较短。与未处理的犊牛相比,经处理的犊牛卵囊排泄量显著减少,体重损失也显著较少。在第21天,所有犊牛被圈养,在第27天,它们被接种1000万个阿拉巴马艾美耳球虫的孢子化卵囊,并放回同一牧场。部分犊牛仅观察到轻微的临床症状,表明所有组均产生了免疫力。然而,第3天接受处理的犊牛有排泄更多卵囊和体重增加较少的趋势。