Johansen A
Laboratoire de Physique de la Matiere Condensee, Universite de Nice-Sophia Antipolis, France.
J Theor Biol. 1996 Jan 7;178(1):45-51. doi: 10.1006/jtbi.1996.0005.
A cellular automaton conceived as a simple model of disease spreading is investigated. We show that the steady-state of the model is described by a spatial organization of the infectious individuals on fronts and undamped temporal oscillations in the number of infectious individuals. This behaviour is observed both for a deterministic and a stochastic input of susceptible individuals, hence showing that recurrent epidemic behaviour can be persistent without any external forcing. The simplicity of the model suggests that such spatio--temporal behaviour can be obtained from nothing, but a direct transmission mechanism between nearest neighbors provided some mechanism for the introduction of new susceptible individuals, e.g., loss of immunity is present.
研究了一种被视为疾病传播简单模型的细胞自动机。我们表明,该模型的稳态由前沿感染个体的空间组织以及感染个体数量无衰减的时间振荡来描述。对于易感个体的确定性和随机输入,均观察到了这种行为,因此表明反复出现的流行行为在没有任何外部强迫的情况下也可能持续存在。该模型的简单性表明,只要存在一些引入新易感个体的机制,例如存在免疫丧失,那么仅通过最近邻之间的直接传播机制就可以得到这种时空行为。