Glassman S J, Hale M J
Division of Dermatology, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.
Clin Exp Dermatol. 1995 Nov;20(6):480-6. doi: 10.1111/j.1365-2230.1995.tb01383.x.
A 34-year-old woman presented with a history of fever, malaise and skin lesions. A diagnosis of Kaposi's sarcoma and acquired immunodeficiency syndrome (AIDS) was established, and in addition, the skin lesion which was biopsied also demonstrated cryptococcal infection. Disseminated cryptococcosis was later confirmed and the disease ran a florid course. The co-existence of different diseases within the same lesion is a feature of human immunodeficiency virus (HIV) infection, this being the third documented case of simultaneous Kaposi's sarcoma and cutaneous cryptococcosis occurring at the same site in a patient with AIDS. The nature of this co-existence is discussed with reference to the pathogenesis of Kaposi's sarcoma.
一名34岁女性，有发热、不适及皮肤病变病史。确诊为卡波西肉瘤和获得性免疫缺陷综合征（艾滋病），此外，活检的皮肤病变还显示有隐球菌感染。后来证实为播散性隐球菌病，病情发展迅速。同一病变内存在不同疾病是人类免疫缺陷病毒（HIV）感染的一个特征，这是有记录的第三例艾滋病患者同一部位同时发生卡波西肉瘤和皮肤隐球菌病的病例。本文结合卡波西肉瘤的发病机制对这种共存的性质进行了讨论。
