Tobias J D, Lynch A, Garrett J
Department of Child Health, University of Missouri, Columbia 65212, USA.
Pediatr Emerg Care. 1996 Aug;12(4):249-51. doi: 10.1097/00006565-199608000-00003.
To determine the effect of manual ventilation during intrahospital transport on end-tidal carbon dioxide concentrations in children.
Prospective study in children who required tracheal intubation and mechanical ventilation/ hyperventilation to maintain an arterial partial pressure of CO2 (PaCO2) of 25 to 30 torr for control of intracranial pressure.
Pediatric intensive care unit.
During patient transport with manual ventilation, end-tidal CO2 was monitored with a side-streaming aspirating, infrared device. The person responsible for manual ventilation was informed of the current ventilator settings and the need to maintain a PaCO2 of 25 to 30 torr, but was not allowed to see the end-tidal CO2 monitor.
The study population included 12 patients ranging in age from seven months to 14 years (average age 6.9 years) and in weight from 6.5 to 57 kg (average weight 28.9 kg). A total of 1716 end-tidal CO2 values were recorded during 286 minutes of monitoring. Five hundred and thirty-one (31%) of the readings were in the intended range of 25 to 30 torr. Four hundred (23%) were less than 20 torr, 665 (39%) were in the 20 to 24 torr range, and 119 (6.3%) were greater than 30 torr. Only five were greater than 40 torr.
Unintentional hyperventilation occurs during the intrahospital transport of children. End-tidal CO2 values less than 25 torr were noted 62% of the time.
确定院内转运期间手动通气对儿童呼气末二氧化碳浓度的影响。
对需要气管插管和机械通气/过度通气以维持动脉血二氧化碳分压（PaCO2）在25至30托以控制颅内压的儿童进行前瞻性研究。
儿科重症监护病房。
在患者手动通气转运期间，使用旁流式吸气红外设备监测呼气末二氧化碳。负责手动通气的人员被告知当前的呼吸机设置以及维持PaCO2在25至30托的必要性，但不允许查看呼气末二氧化碳监测器。
研究人群包括12名年龄从7个月至14岁（平均年龄6.9岁）、体重从6.5至57千克（平均体重28.9千克）的患者。在286分钟的监测期间共记录了1716个呼气末二氧化碳值。其中531个（31%）读数在25至30托的预期范围内。400个（23%）小于20托，665个（39%）在20至24托范围内，119个（6.3%）大于30托。只有5个大于40托。
儿童院内转运期间会发生无意的过度通气。呼气末二氧化碳值小于25托的情况占62%。
