Orend K H, Heymer B, Pamler R S, Hahn J, Sunder-Plassmann L
Department of Thoracic and Vascular Surgery, University of Ulm, Germany.
Thorac Cardiovasc Surg. 1996 Jun;44(3):132-5. doi: 10.1055/s-2007-1012001.
Experiments were designed to examine the wound healing characteristics at the aorta-endograft interface. Thoracic aneurysms were induced in sheep and excluded by endovascular placement of a selfexpanding stent graft (Corvita Endovascular Graft). After a follow-up of 1, 4, or 12 weeks sheep were sacrificed and the corresponding segments of the aorta were subjected to histological examinations. Histomorphological evaluation of all groups underlined sufficient exclusion of lesions of the aortic wall by endovascular grafting. There was no evidence of proximal or distal leakage, graft dislocation or migration. The results appeared to be evidence that the endoluminal stent graft may be incorporated by the host aortic tissue.
设计实验以检查主动脉-血管内移植物界面的伤口愈合特征。在绵羊身上诱发胸主动脉瘤，并通过植入自膨式支架移植物（Corvita血管内移植物）进行血管腔内修复。随访1、4或12周后，处死绵羊，对相应节段的主动脉进行组织学检查。所有组的组织形态学评估均强调血管腔内移植可充分排除主动脉壁病变。没有近端或远端渗漏、移植物脱位或移位的证据。结果似乎证明腔内支架移植物可能被宿主主动脉组织包埋。
