Maul G G
J Cell Biol. 1977 Aug;74(2):492-500. doi: 10.1083/jcb.74.2.492.
Nuclear structures similar to those of the nuclear pore complex were found on chromosomes. This finding indicates that part of the pore complex is retained by the chromosomes through mitosis in the absence of the nuclear membrane. The formation of approximately the same number of pore complexes in the presence and absence of protein synthesis during the first 4 h after mitosis proves the reassembly rather than new synthesis of the pore complex. The structure of pore complexes reconstructed in the absence of protein synthesis cannot be distinguished from the structure of those of control cells.
在染色体上发现了与核孔复合体相似的核结构。这一发现表明,在没有核膜的情况下,孔复合体的一部分在有丝分裂过程中被染色体保留。在有丝分裂后的前4小时内,无论有无蛋白质合成,形成的孔复合体数量大致相同,这证明了孔复合体是重新组装而非重新合成。在没有蛋白质合成的情况下重建的孔复合体结构与对照细胞的孔复合体结构无法区分。