Greenberg A S, Hasan A, Montalvo B M, Falabella A, Falanga V
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, FL 33136, USA.
J Am Acad Dermatol. 1996 Oct;35(4):566-8. doi: 10.1016/s0190-9622(96)90681-7.
Acute lipodermatosclerosis is characterized by pain and tenderness in the medial aspect of the leg. It is thought to be the result of venous insufficiency and to be the acute counterpart of chronic lipodermatosclerosis, a hallmark of venous disease. However, there is no direct evidence linking acute lipodermatosclerosis to venous disease.
Our purpose was to determine whether acute lipodermatosclerosis is associated with venous insufficiency.
With air plethysmography, we determined the venous filling index, the ejection fraction, and the residual volume fraction in 15 sequential patients with acute lipodermatosclerosis.
Ten of the 15 patients (67%) had at least one abnormal result, eight (53%) had two, and two (13%) had three. In four patients (27%), abnormalities of both reflux and ejection were noted. Duplex venous ultrasonography, in two of the patients with normal results from air plethysmography, showed incompetent perforators at sites of lipodermatosclerosis.
Acute lipodermatosclerosis is associated with objective findings of venous insufficiency in a high percentage of patients. It is likely that this condition is the result of venous disease.
急性脂膜皮肤硬化症的特征是小腿内侧疼痛和压痛。它被认为是静脉功能不全的结果，并且是慢性脂膜皮肤硬化症的急性对应病症，而慢性脂膜皮肤硬化症是静脉疾病的一个标志。然而，尚无直接证据将急性脂膜皮肤硬化症与静脉疾病联系起来。
我们的目的是确定急性脂膜皮肤硬化症是否与静脉功能不全相关。
我们使用空气体积描记法测定了15例连续性急性脂膜皮肤硬化症患者的静脉充盈指数、射血分数和残余容积分数。
15例患者中有10例（67%）至少有一项异常结果，8例（53%）有两项异常，2例（13%）有三项异常。4例患者（27%）同时存在反流和射血异常。在空气体积描记法结果正常的2例患者中，双功能静脉超声检查显示脂膜皮肤硬化症部位的交通静脉功能不全。
在高比例的患者中，急性脂膜皮肤硬化症与静脉功能不全的客观表现相关。这种病症很可能是静脉疾病的结果。
