Lopes P, Sturbois G, Breart G, Sureau C
J Gynecol Obstet Biol Reprod (Paris). 1977 Mar;6(2):271-4.
The authors have studied the action of an intravenous injection of Spasmaverine (Bis gamma phenyl-3-propylethylamine) on the intra-uterine pressure in labour in 20 cases. This study has shown that there is a definite rise in amplitude, in the frequency of contractions, in the uterine activity as expressed in montevideo units and in the basal tone of the uterus in the ten minutes following an injection of 80 mg of Spasmavérine intravenously. The fetal cardiac rhythm was never altered. The authors recommend care in using this substance intravenously when sedation of uterine activity is sought.
作者研究了静脉注射斯帕司维林(双γ-苯基-3-丙基乙胺)对20例分娩时子宫内压力的作用。该研究表明,静脉注射80毫克斯帕司维林后的十分钟内,子宫收缩的幅度、频率、以蒙得维的亚单位表示的子宫活动以及子宫的基础张力均有明显升高。胎儿心律从未改变。作者建议,在寻求子宫活动镇静作用时,静脉使用该药物需谨慎。