人工流产作为后续胎儿丢失的一个风险因素。

Induced abortion as a risk factor for subsequent fetal loss.

作者信息

Infante-Rivard C, Gauthier R

机构信息

Department of Occupational Health, Faculty of Medicine, McGill University, Montréal, Québec, Canada.

出版信息

Epidemiology. 1996 Sep;7(5):540-2.

PMID:8862989

Abstract

The relation between past induced abortions and subsequent fetal loss is still unclear. We report a case-control study with 331 cases of first spontaneous abortion and 993 controls with no previous spontaneous abortion and a normal pregnancy at the same period of pregnancy. In comparison with primigravid women, the odds ratio for a fetal loss in the current one was 1.41 [95% confidence interval (CI) = 0.81-2.43] among women with one previous pregnancy ending in induced abortion, 4.43 (95% CI = 1.46-13.36) among those with two previous induced abortions out of two pregnancies, and 1.35 (95% CI = 0.64-2.82) among women with three or more previous pregnancies ending in one or more induced abortions.

摘要

既往人工流产与随后的胎儿丢失之间的关系仍不明确。我们报告一项病例对照研究，该研究纳入了331例首次自然流产病例以及993例对照，这些对照既往无自然流产史且在同期妊娠时为正常妊娠。与初产妇相比，既往有一次妊娠以人工流产告终的女性，此次妊娠发生胎儿丢失的比值比为1.41[95%置信区间（CI）=0.81 - 2.43]；既往两次妊娠中有两次人工流产的女性，该比值比为4.43（95%CI = 1.46 - 13.36）；既往有三次或更多次妊娠且其中一次或多次以人工流产告终的女性，该比值比为1.35（95%CI = 0.64 - 2.82）。