Ott F, Bollag W, Geiger J M
Zürich, Pharmaceutical Research, Basel, Switzerland.
Dermatology. 1996;192(4):334-6. doi: 10.1159/000246406.
Retinoids were shown to be effective in the treatment of both oral and cutaneous forms of lichen planus.
Confirm the beneficial effect of low doses of oral tretinoin in lichen planus.
Eighteen patients with lichen planus were treated in an open study for up to 19 months. Efficacy and safety data were recorded.
Complete remission was observed in 13 (72%) and marked improvement in 4 (22%) out of 18 patients. Six patients showed moderate and 12 had no side effects.
Tretinoin is a valuable drug when given at low doses to patients with lichen planus who failed to respond to other therapies.
维甲酸已被证明在治疗口腔和皮肤扁平苔藓方面有效。
证实低剂量口服维甲酸治疗扁平苔藓的有益效果。
对18例扁平苔藓患者进行了一项长达19个月的开放性研究治疗。记录疗效和安全性数据。
18例患者中，13例（72%）完全缓解，4例（22%）显著改善。6例患者有中度反应，12例无副作用。
对于对其他治疗无反应的扁平苔藓患者，低剂量给予维甲酸是一种有价值的药物。
