Bac D J
Dept. of Gastroenterology and Hepatology, University Hospital Rotterdam-Dijkzigt, The Netherlands.
Scand J Gastroenterol Suppl. 1996;218:38-42. doi: 10.3109/00365529609094729.
Spontaneous bacterial peritonitis (SBP) is a serious complication in patients with cirrhosis and ascites with a poor prognosis. The survival pattern and the reasons for not performing a liver transplantation after an episode of SBP were analysed.
A retrospective analysis during the period 1987-1992 in a tertiary referral and liver transplantation centre.
Sixty episodes of SBP were diagnosed in 52 patients with ascites. Thirty-two percent of the patients died within 30 days and 78% within 1 year. Forty patients who survived less than 1 year did not receive a liver transplantation for the following reasons: death within 30 days (n = 12), age above 65 years (n = 10), medical contraindications (n = 6), active alcohol abuse (n = 6), refusal of transplantation (n = 2), death while being analysed for, or awaiting transplantation (n = 4). Two patients had an auxiliary liver transplantation but died postoperatively.
SBP is a serious complication in patients with cirrhosis and ascites, with a high first-year mortality and a high recurrence rate. Although long-term survival after an episode of SBP is possible, liver transplantation should be considered for the patients with a progressive liver disease after a first episode of SBP.
自发性细菌性腹膜炎（SBP）是肝硬化腹水患者的一种严重并发症，预后较差。分析了SBP发作后的生存模式及未进行肝移植的原因。
对1987年至1992年期间在一家三级转诊和肝移植中心进行回顾性分析。
52例腹水患者诊断出60次SBP发作。32%的患者在30天内死亡，78%在1年内死亡。40例存活不足1年的患者未接受肝移植，原因如下：30天内死亡（n = 12）、年龄超过65岁（n = 10）、医学禁忌证（n = 6）、持续酗酒（n = 6）、拒绝移植（n = 2）、在接受评估或等待移植时死亡（n = 4）。2例患者接受了辅助性肝移植，但术后死亡。
SBP是肝硬化腹水患者的严重并发症，第一年死亡率高且复发率高。虽然SBP发作后有可能长期存活，但对于首次发作SBP后患有进行性肝病的患者，应考虑肝移植。
