Lagier R
J Rheumatol. 1977 Spring;4(1):65-72.
Three patients are described, each having a malignant bone tumor associated with inflammatory episodes in the adjacent joint. Two of these were sarcomas of the lower end of the femur, and one a metastatic carcinoma in the distal end of the radius. Histologically, the synovium exhibited moderate and non-specific signs of inflammation near the malignant tissue. These cases illustrate the possibility of diagnostic error, either clinically or on microscopic examination of small specimens, especially in punch biopsies.
本文描述了三名患者，他们均患有与相邻关节炎症发作相关的恶性骨肿瘤。其中两名是股骨下端的肉瘤，一名是桡骨远端的转移性癌。组织学上，滑膜在恶性组织附近表现出中度且非特异性的炎症迹象。这些病例说明了临床诊断或小标本显微镜检查出现诊断错误的可能性，尤其是在穿刺活检中。
