He X H
Third Military Medical College, Chongqing.
Zhonghua Zhong Liu Za Zhi. 1990 Jan;12(1):66-8.
A total of 1355 cases of tumors and tumor-like lesions in the bone seen in the three hospitals affiliated to our college in the past 32 years was analysed. Of them, 1170 (86.4%) were primary bone tumors, 31 (2.3%) metastatic and 154 (11.3%) tumor-like lesions of bone. Histologically, the primary bone tumors were mostly chondrogenic and osteogenic. The ratio of benign to malignant tumors was 2.8:1. Peak ages were 11-40 years. Patients with malignant tumors were ten years younger than those with benign tumors. The first three common benign bone tumors were osteochondroma, osteoma and chondroma. The vulnerable sites were tibia, femur and skull. The first three common malignant bone tumors were osteosarcoma, chondrosarcoma and fibrosarcoma with common sites in femur, tibia and humerus. The majority of tumor-like lesions were fibrous-dysplasia, frequently in the femur. These observations are very similar to those reported at home but quite different from those reported from other countries. In our series, the ratio of benign to malignant bone tumors was the highest (2.8:1); giant cell tumor was not among the first three common benign bone tumors; and the first vulnerable site of benign bone tumors was not femur but tibia.
对我校附属三家医院过去32年中所见的1355例骨肿瘤及肿瘤样病变进行了分析。其中,原发性骨肿瘤1170例(86.4%),转移性骨肿瘤31例(2.3%),骨肿瘤样病变154例(11.3%)。组织学上,原发性骨肿瘤大多为软骨源性和成骨性。良性肿瘤与恶性肿瘤的比例为2.8:1。发病高峰年龄为11至40岁。恶性肿瘤患者比良性肿瘤患者年轻10岁。前三类常见的良性骨肿瘤为骨软骨瘤、骨瘤和软骨瘤。好发部位为胫骨、股骨和颅骨。前三类常见的恶性骨肿瘤为骨肉瘤、软骨肉瘤和纤维肉瘤,好发部位为股骨、胫骨和肱骨。大多数肿瘤样病变为骨纤维异常增殖症,常见于股骨。这些观察结果与国内报道的非常相似,但与其他国家报道的有很大不同。在我们的系列研究中,良性骨肿瘤与恶性骨肿瘤的比例最高(2.8:1);骨巨细胞瘤不在前三类常见的良性骨肿瘤之列;良性骨肿瘤的首个好发部位不是股骨而是胫骨。