Pérez Fontán M, Rodríguez-Carmona A, Bouza P, García Falcón T, Adeva M, Valdés F, Oliver J
Nephrology Unit, Hospital Juan Canalejo, A Coruña, Spain.
Adv Perit Dial. 1996;12:101-4.
We have compared the incidence of delayed graft function (DGF) after renal transplantation in our patients undergoing peritoneal dialysis (PD) (group A, n = 92) or hemodialysis (HD) (group B, n = 587), analyzing the prevalence of the main risk factors for DGF in both groups. Both groups were comparable, except for a higher prevalence of diabetes (p < 0.05) and a shorter time on dialysis (p < 0.01) in group A. Immediate graft function occurred in 68.5% of group A and 46.5% of group B, DGF in 22.5% of group A and 39.5% of group B, and there was never any function in 9% of group A and 14% of group B (p < 0.001). When potential risk factors for DGF were compared, no relevant differences could be found. HD was performed more frequently immediately before surgery in group B (p < 0.001), but statistical analysis showed no impact of this measure on the incidence of DGF. In conclusion, in our population, patients on PD present higher rates of immediate graft function after renal transplantation than patients on HD. The explanation for the difference is not clear, but seems to be related to the dialysis modality itself, as the profile of risk factors for DGF is very similar in both populations.
我们比较了接受腹膜透析（PD）的患者（A组，n = 92）和接受血液透析（HD）的患者（B组，n = 587）肾移植后延迟移植肾功能（DGF）的发生率，并分析了两组中DGF主要危险因素的患病率。除A组糖尿病患病率较高（p < 0.05）和透析时间较短（p < 0.01）外，两组具有可比性。A组68.5%的患者移植肾功能立即恢复，B组为46.5%；A组22.5%的患者发生DGF，B组为39.5%；A组9%的患者和B组14%的患者移植肾从未有任何功能（p < 0.001）。比较DGF的潜在危险因素时，未发现相关差异。B组术前更频繁地进行HD（p < 0.001），但统计分析表明该措施对DGF的发生率没有影响。总之，在我们的研究人群中，肾移植后接受PD的患者移植肾功能立即恢复的比例高于接受HD的患者。差异的原因尚不清楚，但似乎与透析方式本身有关，因为两组中DGF的危险因素分布非常相似。
