[Effect of various anti-arrhythmia agents on phase structure of cardiac cycle and ballistocardiograph].

A comparative assessment is presented for the effect of Obsiden, Isoptine, Novocainamide, or Chinidin on the phase structure of the cardiac cycle and on the ballistocardiogramme in 125 patients with arrhythmias of varying forms and genesis. A combined employment of Obsidan or Novocainamide with cardiac glycosides was associated with a worsening of the phase structure of the cardiac cycle; with a similar therapy with Isoptine the poly- and ballistocardiographic data improved significantly. The administration of Isoptine without cardiac glycosides resulted in a distinct impairment of these parameters, although prior to the administration of the drug these patients had no circulatory insufficiency. The observed negative effect of Chinidin upon the indices of poly- and ballistocardiography was substantial following preceeding therapy with Isoptine, and less distinct--following Obsiden treatment.