Walter M, Türler A, Schmitz-Rixen T
Klinik und Poliklinik für Chirurgie, Universität zu Köln.
Zentralbl Chir. 1996;121(3):216-22.
Talc pleurodesis was performed in a prospective trial in 38 patients with recurrent malignant pleural effusion. After insertion of a chest tube a slurry containing 8g of iodined talcum, 0.5 ml of 1% xylocain/kg/body weight, and 80 ml of 0.9% NaCl was administered and suction drainage was performed. The chest tube could be removed after 4 +/- 1.7 days. A successful therapy could be achieved in 33/38 patients (86.8%). 2 patients (5.3%) suffered from recurrent pleural effusion which only in 1 case had to be drained. 3 patients died within the first month after talc pleurodesis due to an advanced cancer stage. Complications did not come to evidence in any case.
在一项前瞻性试验中，对38例复发性恶性胸腔积液患者实施了滑石粉胸膜固定术。插入胸管后，给予含有8克碘化滑石粉、0.5毫升1%利多卡因/千克体重和80毫升0.9%氯化钠的混悬液，并进行负压引流。4±1.7天后可拔除胸管。33/38例患者（86.8%）治疗成功。2例患者（5.3%）出现复发性胸腔积液，仅1例需要引流。3例患者在滑石粉胸膜固定术后第一个月内死于癌症晚期。未出现任何并发症。
