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滑石粉胸膜固定术治疗复发性恶性胸腔积液——一项前瞻性随访研究

[Talc pleurodesis in recurrent malignant pleural effusion--a prospective follow-up study].

作者信息

Walter M, Türler A, Schmitz-Rixen T

机构信息

Klinik und Poliklinik für Chirurgie, Universität zu Köln.

出版信息

Zentralbl Chir. 1996;121(3):216-22.

PMID:8867348
Abstract

Talc pleurodesis was performed in a prospective trial in 38 patients with recurrent malignant pleural effusion. After insertion of a chest tube a slurry containing 8g of iodined talcum, 0.5 ml of 1% xylocain/kg/body weight, and 80 ml of 0.9% NaCl was administered and suction drainage was performed. The chest tube could be removed after 4 +/- 1.7 days. A successful therapy could be achieved in 33/38 patients (86.8%). 2 patients (5.3%) suffered from recurrent pleural effusion which only in 1 case had to be drained. 3 patients died within the first month after talc pleurodesis due to an advanced cancer stage. Complications did not come to evidence in any case.

摘要

在一项前瞻性试验中,对38例复发性恶性胸腔积液患者实施了滑石粉胸膜固定术。插入胸管后,给予含有8克碘化滑石粉、0.5毫升1%利多卡因/千克体重和80毫升0.9%氯化钠的混悬液,并进行负压引流。4±1.7天后可拔除胸管。33/38例患者(86.8%)治疗成功。2例患者(5.3%)出现复发性胸腔积液,仅1例需要引流。3例患者在滑石粉胸膜固定术后第一个月内死于癌症晚期。未出现任何并发症。

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