Anil S, Smaranayake L P, Nair R G, Beena V T
Department of Periodontics, Government Dental College, Trivandrum, India.
Aust Dent J. 1996 Aug;41(4):235-7. doi: 10.1111/j.1834-7819.1996.tb04865.x.
The acute leukaemias are a group of neoplastic diseases that are characterized by proliferation of immature white cells in the bone marrow and/or blood and are often associated with severe leukopenia, anaemia and thrombocytopenia. Oral manifestations are more common in patients with acute leukaemia. Oral bleeding, gingival enlargement, ulceration and infection in patients with leukaemia have been described. Leukaemic infiltrates in the gingivae are commonly seen in acute monocytic leukaemia. A case of acute monocytic leukaemia in a 34-year-old female who reported with gingival enlargement is presented here. The role of oral lesions as a diagnostic indicator is discussed.
急性白血病是一组肿瘤性疾病,其特征是骨髓和/或血液中未成熟白细胞增殖,常伴有严重的白细胞减少、贫血和血小板减少。口腔表现在急性白血病患者中更为常见。白血病患者的口腔出血、牙龈肿大、溃疡和感染已有报道。牙龈白血病浸润常见于急性单核细胞白血病。本文报告一例34岁女性急性单核细胞白血病患者,该患者以牙龈肿大就诊。并讨论了口腔病变作为诊断指标的作用。