Tudzynski P, Esser K
Mol Gen Genet. 1977 May 20;153(1):111-3. doi: 10.1007/BF01036003.
The onset of senescence, i.e. decrease of growth rate followed by cellular death, is prevented when inhibitors of mitochondrial function (ethidium-bromide, streptomycin, tiamulin) are present in the culture medium. If mycelia are transferred to a medium not containing one of these substances, senescence occurs after the usual time interval (30 d at 26 degrees C). Inhibitors of cytoplasmic protein synthesis such as emetine and cycloheximide have no effect in preventing senescence.
当培养基中存在线粒体功能抑制剂（溴化乙锭、链霉素、泰妙菌素）时，衰老的开始，即生长速率下降随后细胞死亡，会受到抑制。如果将菌丝体转移到不含这些物质之一的培养基中，衰老会在通常的时间间隔后（26℃下30天）发生。诸如依米丁和环己酰亚胺等细胞质蛋白质合成抑制剂在防止衰老方面没有作用。
