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A double blind, placebo-controlled study to assess the effect of famciclovir on virus replication in patients with chronic hepatitis B virus infection.

作者信息

Main J, Brown J L, Howells C, Galassini R, Crossey M, Karayiannis P, Georgiou P, Atkinson G, Thomas H C

机构信息

Department of Medicine, St Mary's Hospital Medical School, London, UK.

出版信息

J Viral Hepat. 1996 Jul;3(4):211-5. doi: 10.1111/j.1365-2893.1996.tb00098.x.

Abstract

This is the first double-blind controlled study of famciclovir, an oral antiviral agent, as potential therapy for chronic hepatitis B virus (HBV) carries. A fall of more than 90% in HBV DNA levels was noted in six of 11 evaluable patients treated with a 10 day course of oral famciclovir. Further studies with more prolonged therapy are ongoing.

摘要

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