• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A double blind, placebo-controlled study to assess the effect of famciclovir on virus replication in patients with chronic hepatitis B virus infection.

作者信息

Main J, Brown J L, Howells C, Galassini R, Crossey M, Karayiannis P, Georgiou P, Atkinson G, Thomas H C

机构信息

Department of Medicine, St Mary's Hospital Medical School, London, UK.

出版信息

J Viral Hepat. 1996 Jul;3(4):211-5. doi: 10.1111/j.1365-2893.1996.tb00098.x.

DOI:10.1111/j.1365-2893.1996.tb00098.x
PMID:8871884
Abstract

This is the first double-blind controlled study of famciclovir, an oral antiviral agent, as potential therapy for chronic hepatitis B virus (HBV) carries. A fall of more than 90% in HBV DNA levels was noted in six of 11 evaluable patients treated with a 10 day course of oral famciclovir. Further studies with more prolonged therapy are ongoing.

摘要

相似文献

1
A double blind, placebo-controlled study to assess the effect of famciclovir on virus replication in patients with chronic hepatitis B virus infection.
J Viral Hepat. 1996 Jul;3(4):211-5. doi: 10.1111/j.1365-2893.1996.tb00098.x.
2
Treatment of hepatitis B-related polyarteritis nodosa with famciclovir and interferon alfa-2b.泛昔洛韦与干扰素α-2b联合治疗乙型肝炎相关结节性多动脉炎
J Hepatol. 1997 Apr;26(4):935-9. doi: 10.1016/s0168-8278(97)80263-2.
3
Famciclovir treatment of hepatitis B infection following liver transplantation: a long-term, multi-centre study.
Transpl Infect Dis. 2001 Mar;3(1):16-23. doi: 10.1034/j.1399-3062.2001.003001016.x.
4
[Clinical investigation of famciclovir in chronic hepatitis B patients irresponsive to alpha interferon treatment].
Zhonghua Gan Zang Bing Za Zhi. 2005 Jul;13(7):494-6.
5
Comparison of the efficacy of lamivudine and famciclovir in Asian patients with chronic hepatitis B: results of 24 weeks of therapy.拉米夫定与泛昔洛韦治疗亚洲慢性乙型肝炎患者的疗效比较:24周治疗结果
J Med Virol. 2002 Jul;67(3):334-8. doi: 10.1002/jmv.10075.
6
Comparison of famciclovir and lamivudine in the long-term treatment of hepatitis B infection after liver transplantation.
Transplantation. 2001 Jan 15;71(1):96-101. doi: 10.1097/00007890-200101150-00016.
7
Pretransplant famciclovir as prophylaxis for hepatitis B virus recurrence after liver transplantation.
Transplantation. 1997 May 27;63(10):1415-9. doi: 10.1097/00007890-199705270-00008.
8
Famciclovir therapy for recurrent hepatitis B virus infection after liver transplantation.泛昔洛韦治疗肝移植后复发性乙型肝炎病毒感染
Transpl Int. 1996;9 Suppl 1:S210-2. doi: 10.1007/978-3-662-00818-8_53.
9
Combination therapy with famciclovir and interferon-alpha for the treatment of chronic hepatitis B.泛昔洛韦与α干扰素联合治疗慢性乙型肝炎
J Infect Dis. 1998 Nov;178(5):1483-7. doi: 10.1086/314430.
10
Prostaglandin E plus famciclovir--a new concept for the treatment of severe hepatitis B after liver transplantation.前列腺素E联合泛昔洛韦——肝移植后重症乙型肝炎治疗的新概念
Transplantation. 1994 Jun 27;57(12):1706-8.

引用本文的文献

1
Sexually acquired hepatitis.性传播性肝炎
Sex Transm Infect. 2002 Aug;78(4):235-40. doi: 10.1136/sti.78.4.235.
2
Cross-resistance testing of antihepadnaviral compounds using novel recombinant baculoviruses which encode drug-resistant strains of hepatitis B virus.使用编码乙型肝炎病毒耐药株的新型重组杆状病毒进行抗乙肝病毒化合物的交叉耐药性检测。
Antimicrob Agents Chemother. 2001 Jun;45(6):1705-13. doi: 10.1128/AAC.45.6.1705-1713.2001.
3
Comparison of sequence analysis and the INNO-LiPA HBV DR line probe assay for detection of lamivudine-resistant hepatitis B virus strains in patients under various clinical conditions.
序列分析与INNO-LiPA HBV DR线性探针检测法在不同临床条件下患者中检测拉米夫定耐药乙型肝炎病毒株的比较。
J Clin Microbiol. 2001 May;39(5):1972-4. doi: 10.1128/JCM.39.5.1972-1974.2001.
4
Combination chemotherapy for hepatitis B virus: the path forward?乙型肝炎病毒的联合化疗:未来之路?
Drugs. 2000 Sep;60(3):517-31. doi: 10.2165/00003495-200060030-00001.
5
Treatment of chronic hepatitis B: new antiviral therapies.慢性乙型肝炎的治疗:新的抗病毒疗法
Curr Gastroenterol Rep. 1999 Feb-Mar;1(1):20-6. doi: 10.1007/s11894-999-0082-7.
6
Development of resistance and perspectives for future therapies against hepatitis B infections: lessons to be learned from HIV.乙型肝炎感染耐药性的发展及未来治疗前景:从艾滋病病毒中吸取的教训
Infection. 1999;27 Suppl 2:S45-51. doi: 10.1007/BF02561672.
7
In vitro antihepadnaviral activities of combinations of penciclovir, lamivudine, and adefovir.喷昔洛韦、拉米夫定和阿德福韦联合用药的体外抗乙肝病毒活性
Antimicrob Agents Chemother. 2000 Mar;44(3):551-60. doi: 10.1128/AAC.44.3.551-560.2000.
8
Line probe assay for monitoring drug resistance in hepatitis B virus-infected patients during antiviral therapy.用于监测乙型肝炎病毒感染患者抗病毒治疗期间耐药性的线性探针分析。
J Clin Microbiol. 2000 Feb;38(2):702-7. doi: 10.1128/JCM.38.2.702-707.2000.
9
Recent advances in antiviral therapy.抗病毒治疗的最新进展。
J Clin Pathol. 1999 Feb;52(2):89-94. doi: 10.1136/jcp.52.2.89.
10
Inhibition of duck hepatitis B virus replication by 9-(2-phosphonylmethoxyethyl)adenine, an acyclic phosphonate nucleoside analogue.无环膦酸核苷类似物9-(2-膦酰甲氧基乙基)腺嘌呤对鸭乙型肝炎病毒复制的抑制作用
Antimicrob Agents Chemother. 1998 Dec;42(12):3130-5. doi: 10.1128/AAC.42.12.3130.