Main J, Brown J L, Howells C, Galassini R, Crossey M, Karayiannis P, Georgiou P, Atkinson G, Thomas H C
Department of Medicine, St Mary's Hospital Medical School, London, UK.
J Viral Hepat. 1996 Jul;3(4):211-5. doi: 10.1111/j.1365-2893.1996.tb00098.x.
This is the first double-blind controlled study of famciclovir, an oral antiviral agent, as potential therapy for chronic hepatitis B virus (HBV) carries. A fall of more than 90% in HBV DNA levels was noted in six of 11 evaluable patients treated with a 10 day course of oral famciclovir. Further studies with more prolonged therapy are ongoing.