Buonomo E, Pasquarella A, Palombi L
Chair of Hygiene, University Tor Vergata, Rome, Italy.
J Hum Hypertens. 1996 Sep;10 Suppl 3:S77-9.
In an investigation on hypertension risk factors, the entire school population was examined in Trecchina, a southern Italian village. The reported findings refer to those children examined together with at least one parent, for a total of 134 mother-child pairs and 128 father-child pairs. For these groups of children, fathers and mothers, systolic (SBP) and diastolic (DBP) blood pressure, weight (W), height (H) and triceps skinfold (TS) were detected and body mass index (BMI) was calculated in order to evaluate the prevalence of high blood pressure (BP) values and if overweight. Of 19.3% children, 26.9% fathers and 15.8% mothers showed high BP values; 28.9% of children, 14.0% of fathers and 19.3% of mothers were overweight. In children, the analysis of correlations, after adjustment for height, showed a significant association between BP and W, BMI and TS. Using multiple regression analysis, with BP as the dependent variable, SBP was significantly associated with BMI and age in mother and fathers. For DBP the only variable entered in the model was BMI for mothers and fathers. When controlling for the children's age, H, W and BMI of children were significantly related to H, W and BMI of mothers and fathers. These results confirm that overweight and a parental history of obesity are predictive and possibly causal factors for essential hypertension.
在一项关于高血压风险因素的调查中，意大利南部村庄特雷奇纳的全体在校学生都接受了检查。报告的研究结果涉及那些与至少一位家长一起接受检查的儿童，共有134对母子和128对父子。对于这些儿童、父亲和母亲群体，检测了收缩压（SBP）和舒张压（DBP）、体重（W）、身高（H）和肱三头肌皮褶厚度（TS），并计算了体重指数（BMI），以评估高血压值的患病率以及是否超重。19.3%的儿童、26.9%的父亲和15.8%的母亲血压值偏高；28.9%的儿童、14.0%的父亲和19.3%的母亲超重。在儿童中，在对身高进行调整后，相关性分析显示血压与体重、BMI和TS之间存在显著关联。使用多元回归分析，以血压作为因变量，收缩压在母亲和父亲中与BMI和年龄显著相关。对于舒张压，模型中纳入的唯一变量是母亲和父亲的BMI。在控制儿童年龄后，儿童的身高、体重和BMI与母亲和父亲的身高、体重和BMI显著相关。这些结果证实超重和父母肥胖史是原发性高血压的预测因素，可能也是致病因素。
