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肾移植中尸体器官捐献的当代标准:对更好的选择参数的需求。

Contemporary criteria for cadaveric organ donation in renal transplantation: the need for better selection parameters.

作者信息

Taylor R J, Engelsgjerd J S

机构信息

University of Nebraska Medical Center, Omaha 68198-2360, USA.

出版信息

World J Urol. 1996;14(4):225-9. doi: 10.1007/BF00182071.

DOI:10.1007/BF00182071
PMID:8873435
Abstract

A major problem facing transplantation is the disparity between the availability of cadaver donors and the number of recipients awaiting transplantation. Efforts to deal with this issue have involved the use of "marginal donors." Results obtained using these organs have often been significantly worse at 1 and 3 years of follow-up. The problem of how to select and utilize these donors is of critical importance to both patients and society. Current criteria available for assessing cadaver donors are based on ideal donors. Although these appear adequate for predicting the results for the ideal donor, they are not adequate for assessing results for marginal donors. New criteria are of critical importance for better utilization of these organs. The purpose of this review is to examine the current criteria for ideal and marginal donors, review the critical issues to be clarified, and discuss options for improvement results in the future.

摘要

移植面临的一个主要问题是尸体供体的可获得性与等待移植的受者数量之间的差距。解决这一问题的努力涉及使用“边缘供体”。使用这些器官获得的结果在1年和3年的随访中往往明显更差。如何选择和利用这些供体的问题对患者和社会都至关重要。目前可用于评估尸体供体的标准是基于理想供体制定的。虽然这些标准似乎足以预测理想供体的结果,但它们不足以评估边缘供体的结果。新的标准对于更好地利用这些器官至关重要。本综述的目的是研究理想供体和边缘供体的当前标准,回顾需要澄清的关键问题,并讨论未来改善结果的选择。

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1
Contemporary criteria for cadaveric organ donation in renal transplantation: the need for better selection parameters.肾移植中尸体器官捐献的当代标准:对更好的选择参数的需求。
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本文引用的文献

1
Long-term follow-up of recipients of cadaver kidney allografts from elderly donors.老年供体尸体肾移植受者的长期随访
Transplant Proc. 1993 Dec;25(6):3175-6.
2
The hyperfiltration hypothesis in human renal transplantation.人类肾移植中的高滤过假说
Transplantation. 1994 May 27;57(10):1450-4.
3
Expanded criteria for cadaver organ donation in renal transplantation.肾移植中尸体器官捐赠的扩大标准。
Urol Clin North Am. 1994 May;21(2):283-92.
4
The UNOS Scientific Renal Transplant Registry.器官共享联合网络科学肾脏移植登记处。
Clin Transpl. 1993:1-18.
5
Transplantation of kidneys from hypertensive cadaveric donors.来自高血压尸体供体的肾脏移植。
Transplant Proc. 1995 Feb;27(1):989-90.
6
Five-year follow-up of 250 recipients of cadaveric kidney allografts from donors older than 55 years of age.对250名接受55岁以上供体尸体肾移植受者的五年随访。
Transplant Proc. 1995 Feb;27(1):981-3.
7
Optimal use for older donor kidneys: older recipients.老年供肾的最佳用途:老年受者。
Transplant Proc. 1995 Feb;27(1):801-2.
8
Remarkable accuracy of a new cadaveric donor evaluation tool.一种新型尸体供体评估工具具有显著的准确性。
Transplant Proc. 1995 Feb;27(1):797-9.
9
HLA matching determines susceptibility to harmful effects of delayed graft function in renal transplant recipients.人类白细胞抗原(HLA)配型决定肾移植受者发生移植肾功能延迟恢复有害影响的易感性。
Transplant Proc. 1995 Feb;27(1):1068-9.
10
Increased incidence of rejection in patients with delayed graft function.移植肾功能延迟恢复患者排斥反应发生率增加。
Clin Transplant. 1994 Dec;8(6):527-31.