Taylor R J, Engelsgjerd J S
University of Nebraska Medical Center, Omaha 68198-2360, USA.
World J Urol. 1996;14(4):225-9. doi: 10.1007/BF00182071.
A major problem facing transplantation is the disparity between the availability of cadaver donors and the number of recipients awaiting transplantation. Efforts to deal with this issue have involved the use of "marginal donors." Results obtained using these organs have often been significantly worse at 1 and 3 years of follow-up. The problem of how to select and utilize these donors is of critical importance to both patients and society. Current criteria available for assessing cadaver donors are based on ideal donors. Although these appear adequate for predicting the results for the ideal donor, they are not adequate for assessing results for marginal donors. New criteria are of critical importance for better utilization of these organs. The purpose of this review is to examine the current criteria for ideal and marginal donors, review the critical issues to be clarified, and discuss options for improvement results in the future.
移植面临的一个主要问题是尸体供体的可获得性与等待移植的受者数量之间的差距。解决这一问题的努力涉及使用“边缘供体”。使用这些器官获得的结果在1年和3年的随访中往往明显更差。如何选择和利用这些供体的问题对患者和社会都至关重要。目前可用于评估尸体供体的标准是基于理想供体制定的。虽然这些标准似乎足以预测理想供体的结果,但它们不足以评估边缘供体的结果。新的标准对于更好地利用这些器官至关重要。本综述的目的是研究理想供体和边缘供体的当前标准,回顾需要澄清的关键问题,并讨论未来改善结果的选择。