Lusiani L, Visonà A, Bonanome A, Pesavento R, Zanco P
Cattedra di Medicina Interna, Università di Padova, Italy.
Chest. 1996 Oct;110(4):996-1000. doi: 10.1378/chest.110.4.996.
To evaluate whether pulmonary embolism (PE), as detected by perfusion lung scan, could be predicted by the ultrasonic (US) characteristics of the thrombi in patients with deep venous thrombosis (DVT) of the lower limbs.
Ninety-three consecutive patients with DVT and no symptoms of lung involvement (52 men, 41 women; mean age, 67 +/- 17 years).
The degree of thrombotic involvement of the lower limbs was assessed using a US score system ranging from 1 (indicating a subsegmental, nonocclusive thrombus) to 16 (massive, occlusive). According to the echographic and color-Doppler features, the thrombi were classified in terms of echoreflectivity, adhesiveness to the vein wall, and organization. The diagnosis of PE (PIOPED criteria) was highly probable in 46% of the patients, intermediate in 15%, low in 8%, and very low/normal in 31%. No correlations were found between the lung scan findings on one side and the venous scoring system or the US features of the thrombi on the other side.
While confirming that the prevalence of PE in patients with DVT is elevated, we failed to define a subgroup of patients at higher risk. Our data imply that lung scan should be used extensively for the detection of silent PE and that anticoagulation should not be graded on US findings.
评估通过灌注肺扫描检测到的肺栓塞(PE)能否通过下肢深静脉血栓形成(DVT)患者血栓的超声(US)特征进行预测。
93例连续的DVT患者,无肺部受累症状(男52例,女41例;平均年龄67±17岁)。
使用US评分系统评估下肢血栓形成的程度,范围从1分(表示亚段性、非闭塞性血栓)到16分(大块性、闭塞性)。根据超声心动图和彩色多普勒特征,血栓按回声反射性、与静脉壁的粘连性及机化程度进行分类。PE诊断(PIOPED标准)在46%的患者中高度可能,15%为中度可能,8%为低度可能,31%为极低/正常可能。未发现一侧的肺扫描结果与另一侧的静脉评分系统或血栓的US特征之间存在相关性。
虽然证实DVT患者中PE的患病率升高,但我们未能确定高危患者亚组。我们的数据表明,肺扫描应广泛用于检测无症状PE,并且不应根据US检查结果分级进行抗凝治疗。