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钕钇铝石榴石激光膜切开术治疗糖尿病性黄斑前致密出血后黄斑病变的识别

Identifying maculopathy after neodymium: YAG membranotomy for dense diabetic premacular hemorrhage.

作者信息

Ezra E, Dowler J G, Burgess F, Sehmi K, Hamilton P A

机构信息

Medical Retina Service, Moorfields Eye Hospital, London, United Kingdom.

出版信息

Ophthalmology. 1996 Oct;103(10):1568-74. doi: 10.1016/s0161-6420(96)30461-2.

Abstract

PURPOSE

To assess the value of neodymium:YAG membranotomy in achieving rapid intravitreal dispersion of dense diabetic premacular hemorrhage and allowing the identification and treatment of maculopathy before panretinal photocoagulation (PRP).

METHODS

A pilot study, in which nine eyes with dense diabetic premacular hemorrhages were treated with neodymium:YAG membranotomy, is described. After intravitreal dispersion of premacular blood, fundus examination and fluorescein angiography were performed to identify neovascularization and macular edema. Macular photocoagulation was performed before PRP in eyes with co-existing maculopathy and neovascularization.

RESULTS

Complete intravitreal dispersion was achieved in all eyes within 1 week. Clinically significant macular edema was identified and treated, before PRP, in three eyes. No exacerbation of macular edema occurred after PRP, and visual acuity was stabilized at pre-hemorrhage levels in seven eyes and to within one line in the remaining two eyes. No traction retinal detachments or rebleeding occurred, and vitrectomy was not required in any eye.

CONCLUSIONS

Early neodymium:YAG membranotomy may obviate the need for early vitrectomy for dense diabetic premacular hemorrhage, and allows early identification and treatment of maculopathy, before PRP, thus reducing the risk of exacerbation after PRP. Further studies to evaluate this treatment modality, particularly with respect to long-term visual prognosis, appear warranted.

摘要

目的

评估钕:钇铝石榴石膜切开术在实现致密糖尿病性黄斑前出血快速玻璃体腔内分散以及在全视网膜光凝(PRP)之前识别和治疗黄斑病变方面的价值。

方法

描述了一项前瞻性研究,其中对9只患有致密糖尿病性黄斑前出血的眼睛进行了钕:钇铝石榴石膜切开术。在黄斑前血液玻璃体腔内分散后,进行眼底检查和荧光素血管造影以识别新生血管形成和黄斑水肿。对同时存在黄斑病变和新生血管形成的眼睛在PRP之前进行黄斑光凝。

结果

所有眼睛在1周内均实现了完全的玻璃体腔内分散。在3只眼睛中,在PRP之前识别并治疗了具有临床意义的黄斑水肿。PRP后未发生黄斑水肿加重,7只眼睛的视力稳定在出血前水平,其余2只眼睛的视力稳定在相差一行以内。未发生牵引性视网膜脱离或再出血,任何眼睛均无需进行玻璃体切除术。

结论

早期钕:钇铝石榴石膜切开术可能无需因致密糖尿病性黄斑前出血而早期进行玻璃体切除术,并允许在PRP之前早期识别和治疗黄斑病变,从而降低PRP后病情加重的风险。有必要进行进一步研究以评估这种治疗方式,特别是关于长期视觉预后。

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