Uchida Y, Kawai A, Taguchi K, Yokoi T, Pu J, Inoue H
Department of Orthopaedic Surgery, Okayama University Medical School, Japan.
Acta Med Okayama. 1996 Aug;50(4):191-6. doi: 10.18926/AMO/30472.
We conducted a clinicopathological analysis of chondrosarcomas in 17 patients treated in our institute. The 5- and 10-year overall survival rates of the patients were 72.3% and 61.9%, respectively. The significant prognostic factors were size and histologic grade of the tumor. Sex, age, location of the primary tumor, or the presence of a preceding exostosis did not affect the treatment results significantly. Chondrosarcomas of histologic grades I and II did not metastasize, while all grade III and dedifferentiated chondrosarcomas metastasized to the lung. The local recurrence rate depended on the surgical margin. Wide excision with an adequate surgical margin is important to achieve local control of the chondrosarcoma.
我们对在我院接受治疗的17例软骨肉瘤患者进行了临床病理分析。患者的5年和10年总生存率分别为72.3%和61.9%。重要的预后因素是肿瘤的大小和组织学分级。性别、年龄、原发肿瘤部位或既往是否存在外生骨疣对治疗结果无显著影响。组织学I级和II级的软骨肉瘤未发生转移,而所有III级和去分化软骨肉瘤均转移至肺部。局部复发率取决于手术切缘。采用足够的手术切缘进行广泛切除对于实现软骨肉瘤的局部控制很重要。