Fujisaka M, Ohtani O, Watanabe Y
Department of Anatomy, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Arch Histol Cytol. 1996 Aug;59(3):273-80. doi: 10.1679/aohc.59.273.
The distribution of lymphatics in human palatine tonsils was studied by enzyme-histochemistry for 5'-nucleotidase (5'-Nase) and scanning electron microscopy (SEM) of lymphatic corrosion casts. The palatine tonsils were found to possess lymphatics in the parafollicular area (i.e., interfollicular, interfolliculo-septal, and folliculo-septal area), in the connective tissue septa, and in the capsules, but not in the subepithelial area between the follicles and the follicle-associated epithelia or within the follicles. The tubular lymphatics originated some 200-300 microns below the epithelium and formed a three-dimensional network in the parafollicular area. Some lymphatics around the lower part of the follicle were flat, wide, and irregular in shape, and thus appeared to be lymphatic sinuses, referred to as perifollicular lymphatic sinuses. The lymphatics in the parafollicular area drained into the septal lymphatics, which ran rather straight in the connective tissue septa. The septal lymphatics finally gathered into the broader capsular lymphatics. Most of the septal and capsular lymphatics were endowed with valves. Our results indicate that lymphocytes and fluid from the follicles and the subepithelial region enter the perifollicular lymphatic sinuses and/or the interfollicular lymphatics, pass through the interfolliculo- and folliculo-septal lymphatics, and finally enter the septal and capsular lymphatics to leave the tonsil.
通过5'-核苷酸酶（5'-Nase）的酶组织化学和淋巴管铸型扫描电子显微镜（SEM）研究了人类腭扁桃体中淋巴管的分布。发现腭扁桃体在滤泡旁区域（即滤泡间、滤泡间-间隔和滤泡-间隔区域）、结缔组织间隔和被膜中存在淋巴管，但在滤泡与滤泡相关上皮之间的上皮下区域或滤泡内不存在淋巴管。管状淋巴管起源于上皮下方约200-300微米处，并在滤泡旁区域形成三维网络。滤泡下部周围的一些淋巴管扁平、宽阔且形状不规则，因此似乎是淋巴窦，称为滤泡周淋巴窦。滤泡旁区域的淋巴管汇入间隔淋巴管，间隔淋巴管在结缔组织间隔中走行较为笔直。间隔淋巴管最终汇入更宽阔的被膜淋巴管。大多数间隔和被膜淋巴管都有瓣膜。我们的结果表明，来自滤泡和上皮下区域的淋巴细胞和液体进入滤泡周淋巴窦和/或滤泡间淋巴管，穿过滤泡间和滤泡-间隔淋巴管，最终进入间隔和被膜淋巴管以离开扁桃体。
