Lawson D H, MacDonald S
Postgrad Med J. 1977 Jun;53(620):306-9. doi: 10.1136/pgmj.53.620.306.
Information from a comprehensive drug surveillance programme is analysed to provide details of antibacterial drug use in medical wards. Some 28% of patients received antibacterial therapy, usually for the treatment of respiratory or urinary tract infections. The agents most frequently prescribed were ampicillin, co-trimoxazole and tetracyclines. Overall, 11% of recipients experienced one or more adverse effect of therapy. No significant bacterial growth was obtained from some 40% of specimens of sputum sent from patients. A plea is made for more rational use both of sputum culture in the investigation of patients with respiratory infection and of antibiotics in their treatment.
对一项全面药物监测计划的信息进行分析，以提供内科病房抗菌药物使用的详细情况。约28%的患者接受了抗菌治疗，通常用于治疗呼吸道或尿路感染。最常处方的药物是氨苄西林、复方新诺明和四环素。总体而言，11%的接受治疗者出现了一种或多种治疗不良反应。约40%的患者痰液标本未获得显著细菌生长。有人呼吁在呼吸道感染患者的调查中更合理地使用痰培养，并在治疗中更合理地使用抗生素。
