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The role of interleukin-1 in the pathogenesis of IDDM.

作者信息

Mandrup-Poulsen T

机构信息

Steno Diabetes Center, Gentofte, Denmark.

出版信息

Diabetologia. 1996 Sep;39(9):1005-29. doi: 10.1007/BF00400649.

DOI:10.1007/BF00400649
PMID:8877284
Abstract
摘要

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The role of interleukin-1 in the pathogenesis of IDDM.白细胞介素-1在胰岛素依赖型糖尿病发病机制中的作用。
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2
The role of interleukin-1 in the pathogenesis of insulin-dependent diabetes mellitus.
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4
Dendritic cells in the autoimmune insulitis in NOD mouse models of diabetes.糖尿病NOD小鼠模型自身免疫性胰岛炎中的树突状细胞。
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Immune cells, pancreas development, regeneration and type 1 diabetes.免疫细胞、胰腺发育、再生与1型糖尿病
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[Interleukin-1 and nitric oxide involved in the pathogenesis of diabetes)].[白细胞介素-1和一氧化氮参与糖尿病发病机制]
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[An animal model of type 1 diabetes (NOD mice)].
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Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric-oxide.细胞因子诱导的转化鼠成纤维细胞凋亡涉及内源性一氧化氮的合成。
Int J Oncol. 1993 Dec;3(6):1043-8. doi: 10.3892/ijo.3.6.1043.
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Interleukin-1beta-mediated beta-cell inhibition in vivo.
Dan Med Bull. 1996 Feb;43(1):39-57.
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Antibodies to glutamic acid decarboxylase induced by interferon-alpha therapy for chronic viral hepatitis.α-干扰素治疗慢性病毒性肝炎诱导产生的谷氨酸脱羧酶抗体
Diabetologia. 1996 Jan;39(1):126. doi: 10.1007/BF00400426.
Diabetes Obes Metab. 2025 Jan;27(1):7-22. doi: 10.1111/dom.15991. Epub 2024 Oct 2.
4
β-Cell-selective regulation of gene expression by nitric oxide.一氧化氮对β细胞基因表达的选择性调节。
Am J Physiol Regul Integr Comp Physiol. 2024 Jun 1;326(6):R552-R566. doi: 10.1152/ajpregu.00240.2023. Epub 2024 Apr 8.
5
Correlation analysis between cytokines' profile, autoimmune antibodies and the duration of type 1 diabetes: A case control study in a specialized children's centre in Riyadh.细胞因子谱、自身抗体与 1 型糖尿病病程的相关性分析：利雅得一家专门儿童医院的病例对照研究。
Int J Immunopathol Pharmacol. 2023 Jan-Dec;37:3946320231209821. doi: 10.1177/03946320231209821.
6
The association between diet quality index-international and inflammatory markers in Iranian overweight and obese women.伊朗超重和肥胖女性的国际饮食质量指数与炎症标志物之间的关联。
Front Nutr. 2023 May 19;10:1164281. doi: 10.3389/fnut.2023.1164281. eCollection 2023.
7
Maternal diabetes negatively impacts fetal health.母亲糖尿病对胎儿健康有负面影响。
Open Biol. 2022 Sep;12(9):220135. doi: 10.1098/rsob.220135. Epub 2022 Sep 21.
8
ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic Female NOD Mice and Is Rapidly Upregulated by NF-κB in Pancreatic β-Cells.ICAM-1 丰度在高血糖雌性 NOD 小鼠的胰腺胰岛中增加，并在胰腺 β 细胞中被 NF-κB 快速上调。
J Immunol. 2022 Aug 1;209(3):569-581. doi: 10.4049/jimmunol.2200065.
9
Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells.促炎细胞因子诱导人多能干细胞来源的β细胞快速、NO 非依赖性凋亡、趋化介质表达和白细胞介素-32 分泌。
Diabetologia. 2022 May;65(5):829-843. doi: 10.1007/s00125-022-05654-0. Epub 2022 Feb 5.
10
Cytokine and Nitric Oxide-Dependent Gene Regulation in Islet Endocrine and Nonendocrine Cells.胰岛内分泌和非内分泌细胞中细胞因子和一氧化氮依赖的基因调控。
Function (Oxf). 2021 Dec 1;3(1):zqab063. doi: 10.1093/function/zqab063. eCollection 2022.
4
Interleukin-12 gene expression is associated with rapid development of diabetes mellitus in non-obese diabetic mice.白细胞介素-12基因表达与非肥胖糖尿病小鼠糖尿病的快速发展相关。
Diabetologia. 1996 Jan;39(1):119-22. doi: 10.1007/BF00400422.
5
Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM.巨噬细胞源性细胞因子血清水平升高先于胰岛素依赖型糖尿病（IDDM）发病并伴随其发生。
Diabetologia. 1996 Jan;39(1):60-9. doi: 10.1007/BF00400414.
6
Interleukin-1 beta induces the expression of hsp70, heme oxygenase and Mn-SOD in FACS-purified rat islet beta-cells, but not in alpha-cells.白细胞介素-1β可诱导经荧光激活细胞分选术（FACS）纯化的大鼠胰岛β细胞中热休克蛋白70（hsp70）、血红素加氧酶和锰超氧化物歧化酶（Mn-SOD）的表达，但对α细胞无此作用。
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Diabetes. 1996 Jun;45(6):771-8. doi: 10.2337/diab.45.6.771.
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Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.人类和啮齿动物胰岛中热休克蛋白和抗氧化酶表达的差异：对胰岛素依赖型糖尿病发病机制的影响。
Mol Med. 1995 Nov;1(7):806-20.
9
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Eur J Endocrinol. 1996 Jan;134(1):21-30. doi: 10.1530/eje.0.1340021.
10
Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy.
Cytokine. 1995 Oct;7(7):734-9. doi: 10.1006/cyto.1995.0087.