Tsonis P A, Del Rio-Tsonis K, Wallace J L, Burns J C, Hofmann M C, Millan J L, Washabaugh C H
Department of Biology, University of Dayton 45469-2320, USA.
Int J Dev Biol. 1996 Aug;40(4):813-6.
Recent advances in the field of amphibian limb regeneration have provided insights into its cellular and molecular events. This review summarizes the development of cell lines from limb tissues and their application to the study of transdifferentiation and limb regeneration. In addition, the availability of suitable retroviral vectors for salamanders is discussed for it has opened new avenues for experimentation at the molecular level.
两栖动物肢体再生领域的最新进展为其细胞和分子事件提供了见解。本综述总结了从肢体组织建立细胞系的发展及其在转分化和肢体再生研究中的应用。此外,还讨论了适用于蝾螈的逆转录病毒载体的可用性,因为它为分子水平的实验开辟了新途径。