以严重肝内胆汁淤积为表现的肝淀粉样变性。

Hepatic amyloidosis presenting with severe intrahepatic cholestasis.

作者信息

Goenka M K, Bhasin D K, Vasisth R K, Dhawan S

机构信息

Department of Gastroenterology, Postgraduate Institute of Medical 4ducation and Research, Chandigarh, India.

出版信息

J Clin Gastroenterol. 1996 Sep;23(2):134-6. doi: 10.1097/00004836-199609000-00015.

DOI:10.1097/00004836-199609000-00015

PMID:8877643

Abstract

Systemic amyloidosis presenting with jaundice is rare. A case of primary amyloidosis presenting with severe intrahepatic cholestasis is reported. The patient had hepatomegaly, ascites, and a markedly elevated serum alkaline phosphatase level. He had a rapid downhill course resulting in death. Autopsy showed evidence of amyloidosis involving multiple organs, including the liver, kidney, and heart.

摘要

以黄疸为表现的系统性淀粉样变性很罕见。本文报道了一例以严重肝内胆汁淤积为表现的原发性淀粉样变性病例。该患者有肝肿大、腹水，血清碱性磷酸酶水平显著升高。他病情迅速恶化，最终死亡。尸检显示淀粉样变性累及多个器官，包括肝脏、肾脏和心脏。