银屑病关节炎中拇趾骨膜骨炎的发病率。

Incidence of osteoperiostitis of the great toe in psoriatic arthritis.

作者信息

Goupille P, Védère V, Roulot B, Brunais J, Valat J P

机构信息

Department of Rheumatology, Trousseau Hospital, University of Tours, France.

出版信息

J Rheumatol. 1996 Sep;23(9):1553-6.

PMID:8877924

Abstract

OBJECTIVE

To assess the incidence of osteoperiostitis of the distal phalanx of the great toe in psoriatic arthritis (PsA).

METHODS

One thousand great toes (202 of PsA, 44 of cutaneous psoriasis, 274 of low back pain patients, 296 of rheumatoid arthritis, 136 of spondyloarthropathy, and 48 of connective tissue diseases) were studied for osteoperiostitis of the distal phalanx of the great toe (slight, moderate, or severe), destructive joint lesions of the feet, nail dystrophy, fungal infection, and HLA-B type (patients with PsA).

RESULTS

Osteoperiostitis was observed in 92 great toes. Moderate and severe osteoperiostitis were observed only in PsA. Osteoperiostitis was statistically more frequent in PsA (53/202, 26.2%, especially in those with onychosis: 20/41, 48.8%) than in other groups (39/798, 4.9%) (p < 0.01). In PsA, osteoperiostitis was more frequent in patients with nail dystrophy (20/41, 48.8%) than in patients without (33/161, 20.5%) (p < 0.05). Fungal infection of the nail and HLA haplotype were not associated with osteoperiostitis. In patients with PsA, osteoperiostitis was associated with destructive joint lesions of the feet.

CONCLUSION

Osteoperiostitis of the distal phalanx of the great toe is an enthesopathy evocative of PsA.

摘要

目的

评估银屑病关节炎（PsA）中拇趾远节指骨骨骨膜炎的发生率。

方法

对1000个拇趾（PsA患者202个，皮肤银屑病患者44个，腰痛患者274个，类风湿关节炎患者296个，脊柱关节炎患者136个，结缔组织病患者48个）进行研究，观察拇趾远节指骨的骨骨膜炎（轻度、中度或重度）、足部关节破坏病变、甲营养不良、真菌感染及HLA - B型（PsA患者）。

结果

92个拇趾观察到骨骨膜炎。仅在PsA中观察到中度和重度骨骨膜炎。PsA中骨骨膜炎的发生率在统计学上高于其他组（53/202，26.2%，尤其是有甲病变者：20/41，48.8%）（39/798，4.9%）（p<0.01）。在PsA中，有甲营养不良的患者骨骨膜炎发生率高于无甲营养不良者（20/41，48.8%）（33/161，20.5%）（p<0.05）。甲真菌感染和HLA单倍型与骨骨膜炎无关。在PsA患者中，骨骨膜炎与足部关节破坏病变相关。