兔尿中前列腺素的放射免疫和生物学测定：高钠摄入时PGE2排泄减少。
Radioimmunological and biological measurement of prostaglandins in rabbit urine: decrease of PGE2 excretion at high NaCl intake.
作者信息
Scherer B, Siess W, Weber P C
出版信息
Prostaglandins. 1977 Jun;13(6):1127-39. doi: 10.1016/0090-6980(77)90139-3.
PMID:887801
Abstract
The estimation of prostaglandin (PG) E2 and of PGF2alpha by radioimmunoassay is described in detail. PGE2 was measured after conversion to either PGB2 or PGF2alpha and the results compared to bioassay. The methods were used to follow the excretion of PGE2 and PGF2alpha after salt loading in rabbits. A marked reduction of PGE2 levels was observed at high NaC1 intake, while PGF2alpha excretion remained unchanged.
摘要
详细描述了通过放射免疫测定法对前列腺素（PG）E2和PGF2α的测定。将PGE2转化为PGB2或PGF2α后进行测量，并将结果与生物测定法进行比较。这些方法用于追踪兔子盐负荷后PGE2和PGF2α的排泄情况。在高氯化钠摄入量时观察到PGE2水平显著降低，而PGF2α的排泄保持不变。
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