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巴特综合征:儿童与成人前列腺素排泄的对比模式

Bartter's syndrome: contrasting patterns of prostaglandin excretion in children and adults.

作者信息

Dray F

出版信息

Clin Sci Mol Med. 1978 Jan;54(1):115-8. doi: 10.1042/cs0540115.

Abstract
  1. The daily urine excretion has been studied of prostaglandins (PG) E2 and F2alpha, as measured by radioimmunoassay, in eight children and seven adults with Bartter's syndrome. 2. Excretion of both PGE2 and PGF2alpha was significantly higher in the patients with Bartter's syndrome than in 17 normal children. 3. Twelve normal adults excreted significantly more PGE2 and PGF2alpha than did the normal children. In contrast, adults with Bartter's syndrome did not show an increase in prostaglandin excretion.
摘要
  1. 通过放射免疫测定法,对8名患有巴特综合征的儿童和7名成人的前列腺素(PG)E2和F2α的每日尿排泄量进行了研究。2. 巴特综合征患者中PGE2和PGF2α的排泄量均显著高于17名正常儿童。3. 12名正常成年人排泄的PGE2和PGF2α明显多于正常儿童。相比之下,患有巴特综合征的成年人前列腺素排泄量并未增加。

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