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流行野生麻疹病毒M基因的核苷酸序列及其与亚急性硬化性全脑炎病毒的比较。

Nucleotide sequences of the M gene of prevailing wild measles viruses and a comparison with subacute sclerosing panencephalitis virus.

作者信息

Kai C, Yamanouchi K, Sakata H, Miyashita N, Takahashi H, Kobune F

机构信息

Department of Veterinary Microbiology, University of Tokyo, Japan.

出版信息

Virus Genes. 1996;12(1):85-7. doi: 10.1007/BF00370004.

Abstract

We determined the nucleotide sequences of the coding region for the M gene in seven strains of measles virus (MV) that were isolated in Japan between 1984 and 1993. The mutation found among the seven differed from those of laboratory strains. Many of these mutations were the same as those that are characteristic of SSPE viruses. Thus, we suggest that the mutations that have been considered specific to SSPE virus are in fact consensus among prevailing MV.

摘要

我们测定了1984年至1993年间在日本分离出的7株麻疹病毒(MV)M基因编码区的核苷酸序列。这7株病毒中发现的突变与实验室毒株的突变不同。其中许多突变与亚急性硬化性全脑炎(SSPE)病毒的特征性突变相同。因此,我们认为那些被认为是SSPE病毒特有的突变实际上是流行的麻疹病毒的共有特征。

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