Schumucker D L, Mooney J S, Jones A L
Science. 1977 Sep 2;197(4307):1005-8. doi: 10.1126/science.887935.
Morphometric analysis demonstrated a twofold increase in the surface area of the hepatic endoplasmic reticulum in Fischer 344 rats between 1 and 20 months of age, followed by a significant decrease in this parameter between 20 and 30 months. These changes are attributed to the smooth-surfaced endoplasmic reticulum, since neither the rough-surfaced variety nor the Golgi membranes underwent any significant change in surface area as a function of the age of the animal.
形态计量分析表明，在1至20月龄的Fischer 344大鼠中，肝内质网的表面积增加了两倍，随后在20至30月龄之间该参数显著下降。这些变化归因于光滑表面的内质网，因为粗糙表面的内质网和高尔基体膜的表面积均未随动物年龄的增长而发生任何显著变化。
