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主动脉瘤诱发的弥散性血管内凝血。

Aortic aneurysm-induced disseminated intravascular coagulation.

作者信息

Aboulafia D M, Aboulafia E D

机构信息

Section of Hematology/Oncology, Virginia Mason Medical Center, Seattle, WA 98111, USA.

出版信息

Ann Vasc Surg. 1996 Jul;10(4):396-405. doi: 10.1007/BF02286787.

Abstract

Disseminated intravascular coagulation (DIC) may result in hemorrhagic and thrombotic complications and is rarely associated with stable abdominal aortic aneurysms. In a retrospective review of our experience over the past 5 years, we identified only two instances of DIC-associated abdominal aortic aneurysms among a total of 67 patients who were operated on for asymptomatic aneurysms. In the first patient with DIC induced by abdominal aortic aneurysm, consumptive coagulopathy and a bleeding diathesis developed. The second patient's course was complicated by consumptive coagulopathy and migrating thrombophlebitis. In both instances coagulopathy resolved after surgical intervention. In this report we briefly discuss the pathogenesis and laboratory diagnosis of aneurysm-associated DIC and review current management strategies.

摘要

弥散性血管内凝血(DIC)可能导致出血和血栓形成并发症,并且很少与稳定型腹主动脉瘤相关。在对我们过去5年经验的回顾性研究中,在总共67例接受无症状动脉瘤手术的患者中,我们仅发现2例与DIC相关的腹主动脉瘤。在第一例由腹主动脉瘤诱发DIC的患者中,出现了消耗性凝血病和出血素质。第二例患者的病程并发了消耗性凝血病和游走性血栓性静脉炎。在这两例中,凝血病在手术干预后均得到缓解。在本报告中,我们简要讨论了与动脉瘤相关的DIC的发病机制和实验室诊断,并回顾了当前的管理策略。

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