Epidemiological investigations on viral hepatitis in preschool and school communities. Note II. Evaluation of the prophylactic efficiency of standard gammaglobulin administration.

At the beginning of the 1977--1978 schoolyear 10% standard gammaglobulin (0.03 ml/kg body weight) was administered to 974 preschool children and 530 schoolchildren. Representative groups of children were tested serologically and virologically before gammaglobulin administration and 3 months afterwards. No statistically significant reductions of viral hepatitis morbidity were recorded in the protected groups as against controls.