Zavate O, Ionescu T, Ivan A, Popa S, Angheluţá A, Ungureanu A, Ignea C, Avram G
Virologie. 1978 Apr-Jun;29(2):155-60.
Prophylactic administration of standard gammaglobulin (G) to over 5,000 children led to a more than 6-fold decrease in the incidence of icteric viral hepatitis (V.H.) as compared with the control group and to the disappearance of the autumn--winter epidemic peak. A 3-fold decrease in the incidence of subclinical forms was also achieved. In another group of 5,000 children G was only given to contacts in epidemic foci; the incidence of icteric V. H. was similar to that recorded in controls, while subclinical forms were 2 times more frequent in children having received G after the infectant contact.
对5000多名儿童预防性给予标准丙种球蛋白（G），与对照组相比，黄疸型病毒性肝炎（V.H.）的发病率降低了6倍多，秋冬流行高峰消失。亚临床型的发病率也降低了3倍。在另一组5000名儿童中，仅对疫源地的接触者给予G；黄疸型V.H.的发病率与对照组记录的相似，而在接触感染源后接受G的儿童中，亚临床型的发病率是对照组儿童的2倍。
