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乳酸菌及其噬菌体中的裂解系统。

Lytic systems in lactic acid bacteria and their bacteriophages.

作者信息

Gasson M J

机构信息

Department of Genetics and Microbiology, Institute of Food Research, Norwich Research Park, Colney, UK.

出版信息

Antonie Van Leeuwenhoek. 1996 Oct;70(2-4):147-59. doi: 10.1007/BF00395931.

DOI:10.1007/BF00395931
PMID:8879405
Abstract

Lytic systems of lactic acid bacteria and their bacteriophages are reviewed with an emphasis on molecular characterization. Details of enzyme biochemistry and the cloning and analysis of lytic genes are presented, with coverage of lactococcal prolate headed bacteriophages, lactococcal isometric bacteriophages, Lactobacillus bacteriophages and lactococcal autolysins. Some comments on the importance of autolysis in cheese ripening are included and the biotechnological exploitation of cloned and characterized lytic genes is presented.

摘要

本文综述了乳酸菌及其噬菌体的溶菌系统,重点是分子特征。文中介绍了酶生物化学的细节以及溶菌基因的克隆与分析,内容涵盖乳球菌长头噬菌体、乳球菌等轴噬菌体、乳酸杆菌噬菌体和乳球菌自溶素。文中还对自溶在奶酪成熟过程中的重要性做了一些评论,并介绍了对已克隆和表征的溶菌基因的生物技术利用。

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2
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本文引用的文献

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Autolysis of lactococci: detection of lytic enzymes by polyacrylamide gel electrophoresis and characterization in buffer systems.乳酸菌的自溶:通过聚丙烯酰胺凝胶电泳检测溶菌酶,并在缓冲体系中进行表征。
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Temporally Regulated Transcriptional Expression of the Genomes of Lactococcal Bacteriophages c2 and sk1.
渗漏型乳酸乳球菌培养物可独立于培养物裂解、分泌及输出途径将酶和抗原分泌到细胞外。
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Investigation of the relationship between lysogeny and lysis of Lactococcus lactis in cheese using prophage-targeted PCR.使用噬菌体靶向PCR研究奶酪中乳酸乳球菌的溶原性与裂解之间的关系。
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Identification and characterization of a lysis module present in a large proportion of bacteriophages infecting Streptococcus thermophilus.感染嗜热链球菌的大部分噬菌体中存在的裂解模块的鉴定与表征。
Appl Environ Microbiol. 1999 Feb;65(2):569-77. doi: 10.1128/AEM.65.2.569-577.1999.
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Tailed bacteriophages: the order caudovirales.有尾噬菌体:长尾噬菌体目
Adv Virus Res. 1998;51:135-201. doi: 10.1016/s0065-3527(08)60785-x.
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Analysis of the bacteriolytic enzymes of the autolytic lactococcus lactis subsp. cremoris strain AM2 by renaturing polyacrylamide gel electrophoresis: identification of a prophage-encoded enzyme.通过复性聚丙烯酰胺凝胶电泳分析自溶性乳酸乳球菌乳脂亚种AM2的溶菌酶:一种原噬菌体编码酶的鉴定
Appl Environ Microbiol. 1998 Nov;64(11):4142-8. doi: 10.1128/AEM.64.11.4142-4148.1998.
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Inducible gene expression systems in Lactococcus lactis.乳酸乳球菌中的诱导型基因表达系统。
Mol Biotechnol. 1998 Apr;9(2):127-39. doi: 10.1007/BF02760814.
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Appl Environ Microbiol. 1993 Nov;59(11):3708-12. doi: 10.1128/aem.59.11.3708-3712.1993.
4
Thirteen Virulent and Temperate Bacteriophages of Lactobacillus bulgaricus and Lactobacillus lactis Belong to a Single DNA Homology Group.保加利亚乳杆菌和乳酸乳杆菌的 13 种烈性和温和噬菌体属于单一 DNA 同源群。
Appl Environ Microbiol. 1986 Oct;52(4):812-8. doi: 10.1128/aem.52.4.812-818.1986.
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GROUP N STREPTOCOCCAL PHAGE LYSIN.N群链球菌噬菌体溶素
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Exploitation of a chromosomally integrated lactose operon for controlled gene expression in Lactococcus lactis.利用染色体整合的乳糖操纵子在乳酸乳球菌中进行可控基因表达。
FEMS Microbiol Lett. 1996 Feb 1;136(1):19-24. doi: 10.1016/0378-1097(95)00474-2.
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Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage r1t.温和型乳酸乳球菌噬菌体r1t的序列分析与分子特征
Mol Microbiol. 1996 Mar;19(6):1343-55. doi: 10.1111/j.1365-2958.1996.tb02478.x.
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Inducible gene expression mediated by a repressor-operator system isolated from Lactococcus lactis bacteriophage r1t.由从乳酸乳球菌噬菌体r1t分离的阻遏物-操纵子系统介导的可诱导基因表达。
Mol Microbiol. 1996 Mar;19(6):1331-41. doi: 10.1111/j.1365-2958.1996.tb02477.x.
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Sequencing and analysis of the prolate-headed lactococcal bacteriophage c2 genome and identification of the structural genes.长头乳球菌噬菌体c2基因组的测序与分析及结构基因的鉴定
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Sequence analysis of the lysin gene region of the prolate lactococcal bacteriophage c2.扁长形乳酸乳球菌噬菌体c2裂解酶基因区域的序列分析
Can J Microbiol. 1993 Aug;39(8):767-74. doi: 10.1139/m93-113.