Minami T, Gondo K, Nakayama H, Ueda K
Department of Pediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Brain Dev. 1996 Jul-Aug;18(4):294-8. doi: 10.1016/0387-7604(96)00027-7.
Successful cortical recordings of somatosensory-evoked potentials (SEPs) to posterior tibial nerve (PTN) stimulation were obtained in 21 (87.5%) for P1 and 22 (91.7%) for N1 of 24 infants who were followed up for at least 3 years and had a normal outcome. There were linear decreases with increasing post menstrual age in both P1 and N1 peak latency. Of the four cases with diplegia later, three showed definite abnormalities, no responses and delayed latency in PTN SEPs respectively, however, the other case showed normal responses. Of the three cases with mental retardation, two showed relatively long latency and borderline responses respectively, and the other case showed normal responses. As the pathway of PTN SEPs traverses the periventricular area of the brain likely to be affected by ischemic lesions in premature infants, abnormalities in the responses might indicate a later motor disorder.
在24例至少随访3年且结局正常的婴儿中,21例(87.5%)成功记录到胫后神经(PTN)刺激诱发的体感诱发电位(SEP)的P1波,22例(91.7%)成功记录到N1波。P1波和N1波的峰潜伏期均随孕龄增加呈线性下降。在后来出现双瘫的4例患儿中,3例分别表现为明确异常、无反应及PTN-SEP潜伏期延迟,然而,另一例反应正常。在3例智力发育迟缓的患儿中,2例分别表现为潜伏期相对较长及临界反应,另一例反应正常。由于PTN-SEP的传导通路穿过早产儿脑室内周围区域,该区域易受缺血性病变影响,因此反应异常可能预示后期运动障碍。