经活检证实的肝硬化患者血清胆汁酸水平的放射免疫测定
Radioimmunoassay of serum bile acid levels in biopsy-proved cirrhosis.
作者信息
Dasher C A, Hirschowitz B I, Spenney J G, Gibson R G, Mihas A A
出版信息
South Med J. 1977 Aug;70(8):968-9, 973. doi: 10.1097/00007611-197708000-00020.
Serum bile acid levels were determined by a radioimmunoassay for conjugates of cholic acid in 18 patients with biopsy-proved cirrhosis and compared to results of conventional liver function tests. Serum bile acid levels were abnormal in all 18 patients whereas results of the other tests were abnormal in only 50% to 72% of patients. In this group of patients with a well established diagnosis of cirrhosis, serum bile acid levels were a more sensitive indicator of liver dysfunction than standard liver function tests.
通过放射免疫分析法测定了18例经活检证实为肝硬化患者的血清胆汁酸水平，并与传统肝功能检查结果进行了比较。18例患者的血清胆汁酸水平均异常，而其他检查结果仅在50%至72%的患者中异常。在这组已确诊为肝硬化的患者中，血清胆汁酸水平比标准肝功能检查更能敏感地反映肝功能障碍。
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