Maslow J, Mulligan M E
Veterans' Affairs Medical Center, Boston, Massachusetts, USA.
Infect Control Hosp Epidemiol. 1996 Sep;17(9):595-604. doi: 10.1086/647395.
Microbial strain typing is a useful adjunct to clinical epidemiology. Phenotypic typing systems examine expressed characteristics, whereas genotypic systems, including recent PCR-based systems, examine chromosomal or plasmid DNA. Typing systems have evaluated bacteria, fungi, and viruses successfully. The criteria used to assess the utility of each system include typeability, reproducibility, and discriminatory power.
微生物菌株分型是临床流行病学的一项有用辅助手段。表型分型系统检测表达的特征,而包括最近基于PCR的系统在内的基因型系统检测染色体或质粒DNA。分型系统已成功地用于评估细菌、真菌和病毒。用于评估每个系统实用性的标准包括可分型性、可重复性和鉴别力。