Aizenberg D, Shiloh R, Zemishlany Z, Weizman A
Geha Psychiatric Hospital, Rabin Medical Center, Petah Tiqva, Israel.
J Sex Marital Ther. 1996 Fall;22(3):225-9. doi: 10.1080/00926239608414660.
Male orgasmic disorder is commonly encountered among patients treated with thioridazine. This side effect interferes significantly with sexual satisfaction. In this pilot study, eight male schizophrenic patients who complained of orgasmic disorder, compatible with probable retrograde ejaculation during thioridazine treatment, were given concomitant low-dose imipramine (25-50 mg at bedtime). Four of the eight reported complete resumption of their previous ejaculatory function, and in one patient there was a partial, but substantial, improvement. Three patients noted no change. It appears that imipramine might be beneficial for some patients with thioridazine-induced male orgasmic disorder.
男性性高潮障碍在接受硫利达嗪治疗的患者中很常见。这种副作用会严重影响性满意度。在这项初步研究中，八名抱怨性高潮障碍的男性精神分裂症患者，在硫利达嗪治疗期间可能伴有逆行射精，同时给予低剂量丙咪嗪（睡前25 - 50毫克）。八名患者中有四名报告其先前的射精功能完全恢复，一名患者有部分但显著的改善。三名患者无变化。看来丙咪嗪可能对一些硫利达嗪引起的男性性高潮障碍患者有益。
