Seifert J K, Junginger T
Klinik für Allgemein- und Abdominalchirurgie, Johannes-Gutenberg-Universität Mainz.
Chirurg. 1996 Feb;67(2):161-8.
The records of 30 patients who had hepatic resections for non-colorectal liver metastases between 1985-1994 were analyzed retrospectively. The perioperative morbidity and mortality rates were 7% (2/30) and 3% (1/30). The patient group with curative resection (n = 25) was found to have a 5-year survival rate of 44.6% and a 3-year disease-free survival rate of 19.8%. By univariate analysis, the number of metastases and the amount of perioperative blood replacement were the only factors that affected survival after curative resection. Synchronous vs. metachronous disease was the only factor that showed a significant influence on disease-free survival after curative resection. Although the benefit of liver resection for non-colorectal metastases is limited, surgical therapy can be performed safely and offers some patients a chance of long-time survival.
回顾性分析了1985年至1994年间因非结直肠癌肝转移而接受肝切除术的30例患者的记录。围手术期发病率和死亡率分别为7%(2/30)和3%(1/30)。接受根治性切除术的患者组(n = 25)的5年生存率为44.6%,3年无病生存率为19.8%。单因素分析显示,转移灶数量和围手术期输血量是影响根治性切除术后生存的唯一因素。同时性与异时性疾病是对根治性切除术后无病生存有显著影响的唯一因素。尽管肝切除治疗非结直肠癌转移的益处有限,但手术治疗可以安全进行,并且为一些患者提供了长期生存的机会。