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[113例结直肠癌肝转移患者的肝切除结果]

[Results of liver resection in 113 patients with metastases of colorectal carcinomas].

作者信息

Henne-Bruns D, Vogel I, Kremer B

机构信息

Klinik für Allgemeine Chirurgie und Thoraxchirurgie, Christian-Albrechts-Universität zu Kiel.

出版信息

Zentralbl Chir. 1995;120(2):84-9.

PMID:7709668
Abstract

Between 1985-1991 and 1991-1994 118 liver resections in 113 patients with colorectal liver metastases were performed by our group at the University hospitals of Hamburg and Kiel. The data of 106 patients were analysed regarding the prognostic factors: age, sex, localisation--stage--grading of the primary tumor, localisation--number--size--synchronous/metachronous appearance of metastases, extent and radicality of the liver resection. The results showed, that a significant prognostic influence regarding the long-term survival rate could only be achieved in patients, in which a R0-resection with a histologically proven tumor free margin of more than 1 cm was performed. In these cases (n = 46) a median survival time of 38 months was observed. In patients with histologically proven tumor free resection margins < 1 cm (n = 38) the median survival time was 24 months, in patients with R1-resections (n = 7) 26 months and in patients with R2-resections (n = 15) 20 months respectively.

摘要

1985年至1991年以及1991年至1994年间,我们团队在汉堡和基尔的大学医院对113例结直肠癌肝转移患者进行了118例肝脏切除术。对106例患者的数据进行了分析,涉及预后因素:年龄、性别、原发肿瘤的定位-分期-分级、转移灶的定位-数量-大小-同时性/异时性出现情况、肝脏切除的范围和根治性。结果显示,只有在进行了组织学证实切缘无肿瘤且切缘大于1 cm的R0切除的患者中,才能对长期生存率产生显著的预后影响。在这些病例(n = 46)中,观察到的中位生存时间为38个月。在组织学证实切缘无肿瘤但切缘<1 cm的患者(n = 38)中,中位生存时间为24个月,在进行R1切除的患者(n = 7)中为26个月,在进行R2切除的患者(n = 15)中为20个月。

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