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[应激状态下大鼠肾上腺束状带细胞超微结构的形态计量学研究]

[Morphometric study of the ultrastructure of cells of the zona fasciculata of the adrenals in rats under stress].

作者信息

Gordienko V M, Bogdanova T I, Shvirst E M

出版信息

Tsitologiia. 1977 Feb;19(2):131-6.

PMID:888197
Abstract

A morphometrical study of cell ultrastructures of zona fasciculata of rat adrenal cortex was performed in norm and after immobilization during 4 or 24 hours. A 4 hour's immobilization (alarm reaction) is characterized by adrenocorticocyte activation: relative volumes of mitochondria and reticulum increase by 1.1 and 1.2 times, resp., and lipid volume decrease by 2.6 times. 24 hours after immobilization (the stage of maximal strain), mitochondrion and reticulum volumes decrease by 1.5 and 1.7 times, resp., compared to the initial ones, and autophagosome volumes increase sharply reaching 11% of the cytoplasm volume, i.e. this is the evidence of degeneration clearly registered morphometrically.

摘要

对正常大鼠及固定4小时或24小时后的大鼠肾上腺皮质束状带细胞超微结构进行了形态计量学研究。4小时的固定(警觉反应)以肾上腺皮质细胞激活为特征:线粒体和内质网的相对体积分别增加1.1倍和1.2倍,而脂质体积减少2.6倍。固定24小时后(最大应激阶段),与初始值相比,线粒体和内质网体积分别减少1.5倍和1.7倍,自噬体体积急剧增加,达到细胞质体积的11%,即这是形态计量学明确记录的退化证据。

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